4A2H

Crystal Structure of Laccase from Coriolopsis gallica pH 7.0

Replaces:  2VDS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	LACCASE	polymer	496	52802.4	1	UniProt (Q1W6B1) Pfam (PF07732) Pfam (PF00394) Pfam (PF07731) In PDB	CORIOLOPSIS GALLICA
2	B	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	A	COPPER (II) ION	non-polymer		63.5	4	Chemie (CU)
5	A	beta-D-mannopyranose	non-polymer		180.2	3	Chemie (BMA)
6		water	water		18.0	312	Chemie (HOH)

Sequence modifications

A: 22 - 517 (UniProt: Q1W6B1)

PDB	External Database	Details
Asp 39	Tyr 39	engineered mutation
Asn 151	Gln 151	engineered mutation
Lys 178	Arg 178	engineered mutation
Pro 182	Ala 182	engineered mutation
Val 183	Ile 183	engineered mutation
Tyr 229	His 229	engineered mutation
Leu 256	Ile 256	engineered mutation
Thr 287	Asn 287	engineered mutation
Gln 288	Thr 288	engineered mutation
Thr 294	Val 294	engineered mutation
Thr 314	Ala 314	engineered mutation
Lys 329	Glu 329	engineered mutation
Asn 356	Arg 356	engineered mutation
Thr 358	Ser 358	engineered mutation
Val 423	Ala 423	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	52802.4
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	9
	Total formula weight	1237.1
All*	Total formula weight	54463.9

*Water molecules are not included.