4A0C
Structure of the CAND1-CUL4B-RBX1 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 | polymer | 1253 | 139226.3 | 2 | UniProt (Q86VP6) Pfam (PF13513) Pfam (PF08623) In PDB | HOMO SAPIENS (HUMAN) | CULLIN-ASSOCIATED AND NEDDYLATION-DISSOCIATED PROTEIN 1, TBP-INTERACTING PROTEIN OF 120 KDA A, TBP-INTERACTING PROTEIN 120A, P120 CAND1 |
2 | C, E | CULLIN-4B | polymer | 741 | 86961.3 | 2 | UniProt (Q13620) Pfam (PF00888) Pfam (PF10557) In PDB | HOMO SAPIENS (HUMAN) | CUL-4B |
3 | D, F | E3 UBIQUITIN-PROTEIN LIGASE RBX1 | polymer | 98 | 11330.9 | 2 | UniProt (P62878) Pfam (PF12678) In PDB | MUS MUSCULUS (HOUSE MOUSE) | RING FINGER PROTEIN 75, RING-BOX PROTEIN 1, RBX1 |
4 | D, F | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) |
Sequence modifications
A, B: 1 - 1230 (UniProt: Q86VP6)
C, E: 192 - 913 (UniProt: Q13620)
D, F: 12 - 108 (UniProt: P62878)
PDB | External Database | Details |
---|---|---|
Met -22 | - | expression tag |
Ala -21 | - | expression tag |
Ser -20 | - | expression tag |
Trp -19 | - | expression tag |
Ser -18 | - | expression tag |
His -17 | - | expression tag |
Pro -16 | - | expression tag |
Gln -15 | - | expression tag |
Phe -14 | - | expression tag |
Glu -13 | - | expression tag |
Lys -12 | - | expression tag |
Val -11 | - | expression tag |
Asp -10 | - | expression tag |
Glu -9 | - | expression tag |
Asn -8 | - | expression tag |
Leu -7 | - | expression tag |
Tyr -6 | - | expression tag |
Phe -5 | - | expression tag |
Gln -4 | - | expression tag |
Gly -3 | - | expression tag |
Gly -2 | - | expression tag |
Gly -1 | - | expression tag |
Arg 0 | - | expression tag |
Val 952 | Ala 952 | variant |
PDB | External Database | Details |
---|---|---|
Met 173 | - | expression tag |
His 174 | - | expression tag |
His 175 | - | expression tag |
His 176 | - | expression tag |
His 177 | - | expression tag |
His 178 | - | expression tag |
His 179 | - | expression tag |
Val 180 | - | expression tag |
Asp 181 | - | expression tag |
Glu 182 | - | expression tag |
Asn 183 | - | expression tag |
Leu 184 | - | expression tag |
Tyr 185 | - | expression tag |
Phe 186 | - | expression tag |
Gln 187 | - | expression tag |
Gly 188 | - | expression tag |
Gly 189 | - | expression tag |
Gly 190 | - | expression tag |
Arg 191 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 11 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 475037.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 392.5 | |
All* | Total formula weight | 475429.6 |