4MQE
Crystal structure of the extracellular domain of human GABA(B) receptor in the apo form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Gamma-aminobutyric acid type B receptor subunit 1 | polymer | 420 | 47645.6 | 1 | UniProt (Q9UBS5) Pfam (PF01094) | Homo sapiens (human) | GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1 |
| 2 | B (B) | Gamma-aminobutyric acid type B receptor subunit 2 | polymer | 433 | 49127.5 | 1 | UniProt (O75899) Pfam (PF01094) | Homo sapiens (human) | GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2, G-protein coupled receptor 51, HG20 |
| 3 | C (C) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 1 | In PDB GlyTouCan (G64181RO) | |||
| 4 | D (D) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G47477HI) | |||
| 5 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 246 | Chemie (HOH) |
Sequence modifications
A: 48 - 459 (UniProt: Q9UBS5)
B: 42 - 466 (UniProt: O75899)
| PDB | External Database | Details |
|---|---|---|
| Asp 460 | - | expression tag |
| Tyr 461 | - | expression tag |
| Lys 462 | - | expression tag |
| Asp 463 | - | expression tag |
| Asp 464 | - | expression tag |
| Asp 465 | - | expression tag |
| Asp 466 | - | expression tag |
| Lys 467 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp 467 | - | expression tag |
| Tyr 468 | - | expression tag |
| Lys 469 | - | expression tag |
| Asp 470 | - | expression tag |
| Asp 471 | - | expression tag |
| Asp 472 | - | expression tag |
| Asp 473 | - | expression tag |
| Lys 474 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 96773.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1789.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 98784.0 |
