3ZZH

Crystal structure of the amino acid kinase domain from Saccharomyces cerevisiae acetylglutamate kinase in complex with its feed- back inhibitor L-arginine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	ACETYLGLUTAMATE KINASE	polymer	307	34015.0	4	UniProt (Q01217) Pfam (PF00696)	SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)	N-ACETYLGLUTAMATE KINASE, N-ACETYL-L-GLUTAMATE 5-PHOSPHOTRANSFERASE, NAG KINASE, AGK, PROTEIN ARG5\,6\,MITOCHONDRIAL
2	AA, AB, BA, BB, CA... (B, D, A, C)	1,2-ETHANEDIOL	non-polymer		62.1	45	Chemie (EDO)
3	DA, HB, IB, K, QA (B, D, A, C)	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
4	EA, JB, L (B, D, A)	MALONATE ION	non-polymer		102.0	3	Chemie (MLI)
5	FA, KB, M, RA (B, D, A, C)	N-ACETYL-L-GLUTAMATE	non-polymer		189.2	4	Chemie (NLG)
6	GA (C)	ARGININE	non-polymer		175.2	1	Chemie (ARG)
7	PA (C)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	LB, MB, NB, OB (A, B, C, D)	water	water		18.0	497	Chemie (HOH)

Sequence modifications

A, B, C, D: 58 - 356 (UniProt: Q01217)

PDB	External Database	Details
Met 50	-	expression tag
Gly 51	-	expression tag
His 52	-	expression tag
His 53	-	expression tag
His 54	-	expression tag
His 55	-	expression tag
His 56	-	expression tag
His 57	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	136060.2
Non-Polymers*	Number of molecules	59
	Total formula weight	4300.4
All*	Total formula weight	140360.6

*Water molecules are not included.