Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ARG C 1362 |
| Chain | Residue |
| C | TYR87 |
| C | GLY345 |
| C | MET347 |
| C | HOH2083 |
| C | LYS265 |
| C | SER285 |
| C | GLU337 |
| C | LEU338 |
| C | THR340 |
| C | ASP341 |
| C | SER342 |
| C | GLY343 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1353 |
| Chain | Residue |
| A | ARG169 |
| A | LEU173 |
| A | THR194 |
| A | THR235 |
| A | LEU237 |
| A | MET245 |
| B | SER195 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 1354 |
| Chain | Residue |
| A | ASN76 |
| D | HOH2015 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1355 |
| Chain | Residue |
| A | LYS265 |
| A | ILE266 |
| A | VAL267 |
| A | SER325 |
| A | GLU337 |
| A | HOH2098 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1356 |
| Chain | Residue |
| A | TYR153 |
| A | ASP155 |
| A | GLY156 |
| A | TYR304 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1357 |
| Chain | Residue |
| A | TYR202 |
| A | THR240 |
| A | SER242 |
| A | GLN244 |
| A | HOH2092 |
| A | HOH2094 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1358 |
| Chain | Residue |
| A | VAL252 |
| A | GLU256 |
| A | ARG259 |
| A | GLU312 |
| A | GLU315 |
| A | LEU316 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1359 |
| Chain | Residue |
| A | GLY273 |
| A | LYS283 |
| A | GLY345 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MLI A 1360 |
| Chain | Residue |
| A | ILE157 |
| A | GLY212 |
| A | VAL248 |
| A | ASN249 |
| A | VAL252 |
| A | NLG1361 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE NLG A 1361 |
| Chain | Residue |
| A | GLY135 |
| A | THR136 |
| A | GLY137 |
| A | ARG158 |
| A | ASN247 |
| A | VAL248 |
| A | ASN249 |
| A | ALA250 |
| A | MLI1360 |
| A | HOH2018 |
| A | HOH2019 |
| A | HOH2040 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1351 |
| Chain | Residue |
| A | SER110 |
| A | ASP111 |
| A | HOH2103 |
| B | HOH2012 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1352 |
| Chain | Residue |
| A | SER195 |
| B | ARG169 |
| B | PHE172 |
| B | LEU237 |
| B | MET245 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1353 |
| Chain | Residue |
| B | SER69 |
| B | THR70 |
| B | ALA121 |
| B | PHE122 |
| B | HIS125 |
| B | HOH2046 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1354 |
| Chain | Residue |
| A | LEU173 |
| A | HOH2048 |
| A | HOH2049 |
| B | GLY196 |
| B | THR199 |
| B | THR218 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1355 |
| Chain | Residue |
| A | GLN185 |
| A | HOH2060 |
| B | LYS227 |
| B | ALA228 |
| B | HOH2094 |
| B | HOH2096 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1356 |
| Chain | Residue |
| A | LYS272 |
| B | GLU85 |
| B | LEU88 |
| C | ILE72 |
| C | ASN76 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1357 |
| Chain | Residue |
| B | PRO263 |
| B | SER324 |
| B | HOH2026 |
| B | HOH2134 |
| A | GLN332 |
| B | TYR90 |
| B | GLU262 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1358 |
| Chain | Residue |
| B | GLN96 |
| B | GLN97 |
| B | GLN98 |
| B | LYS219 |
| B | VAL260 |
| B | PHE261 |
| B | HOH2033 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1359 |
| Chain | Residue |
| B | ASN270 |
| B | LYS272 |
| B | LYS309 |
| B | EDO1364 |
| B | HOH2109 |
| B | HOH2142 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1360 |
| Chain | Residue |
| B | ASP161 |
| B | GLU162 |
| B | LYS209 |
| B | HOH2087 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1361 |
| Chain | Residue |
| B | GLN96 |
| B | GLN98 |
| B | GLU223 |
| B | ILE226 |
| B | LYS227 |
| B | HOH2143 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1362 |
| Chain | Residue |
| B | LYS283 |
| B | GLN332 |
| B | ASP333 |
| B | HOH2135 |
| D | ASP111 |
| D | HOH2034 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1363 |
| Chain | Residue |
| B | SER285 |
| B | GLY343 |
| B | ALA344 |
| B | GLY345 |
| B | MET347 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 1364 |
| Chain | Residue |
| B | LYS103 |
| B | ASP251 |
| B | LYS309 |
| B | EDO1359 |
| B | HOH2038 |
| B | HOH2040 |
| B | HOH2099 |
| B | HOH2142 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1365 |
| Chain | Residue |
| B | LEU113 |
| B | HIS114 |
| B | HOH2075 |
| B | HOH2144 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1366 |
| Chain | Residue |
| B | ASP201 |
| B | THR240 |
| B | HOH2082 |
| B | HOH2097 |
| B | HOH2098 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1367 |
| Chain | Residue |
| B | ASN270 |
| B | GLU271 |
| B | HOH2040 |
| B | HOH2142 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MLI B 1368 |
| Chain | Residue |
| B | ILE157 |
| B | GLY212 |
| B | VAL248 |
| B | ASN249 |
| B | HOH2090 |
| site_id | DC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE NLG B 1369 |
| Chain | Residue |
| B | GLY135 |
| B | THR136 |
| B | GLY137 |
| B | ARG158 |
| B | ASN247 |
| B | VAL248 |
| B | ASN249 |
| B | ALA250 |
| B | HOH2038 |
| B | HOH2039 |
| B | HOH2066 |
| B | HOH2068 |
| site_id | DC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1351 |
| Chain | Residue |
| B | SER300 |
| C | ASP152 |
| C | TYR153 |
| D | ALA146 |
| D | GLN147 |
| D | GLY148 |
| site_id | DC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1352 |
| Chain | Residue |
| C | LEU173 |
| C | ASN176 |
| C | PRO192 |
| C | HOH2049 |
| D | PRO221 |
| D | HOH2077 |
| site_id | DC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1353 |
| Chain | Residue |
| C | GLY105 |
| C | ALA107 |
| C | ASN270 |
| C | HOH2015 |
| C | HOH2016 |
| C | HOH2084 |
| site_id | DC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 1354 |
| Chain | Residue |
| A | LYS298 |
| C | ASP111 |
| C | ASN112 |
| C | LEU113 |
| C | HIS114 |
| C | GLU115 |
| C | HOH2020 |
| site_id | DC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 1355 |
| Chain | Residue |
| B | ARG68 |
| B | HOH2006 |
| C | GLY63 |
| C | PHE64 |
| site_id | DC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 1356 |
| Chain | Residue |
| C | LEU144 |
| C | ILE149 |
| C | GLU150 |
| C | ASP161 |
| C | THR164 |
| C | HOH2029 |
| C | HOH2033 |
| C | HOH2034 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1357 |
| Chain | Residue |
| C | ARG169 |
| C | LEU173 |
| C | LEU237 |
| C | MET245 |
| C | HOH2048 |
| D | SER195 |
| site_id | EC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1358 |
| Chain | Residue |
| C | THR67 |
| C | SER69 |
| C | HIS125 |
| C | LEU186 |
| C | HOH2004 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1359 |
| Chain | Residue |
| C | GLY142 |
| C | SER242 |
| C | HOH2058 |
| D | GLU162 |
| D | HOH2064 |
| site_id | EC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 1360 |
| Chain | Residue |
| C | ASN141 |
| D | HOH2066 |
| site_id | EC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE NLG C 1361 |
| Chain | Residue |
| C | GLY135 |
| C | THR136 |
| C | GLY137 |
| C | ARG158 |
| C | ASN247 |
| C | VAL248 |
| C | ASN249 |
| C | ALA250 |
| C | HOH2017 |
| C | HOH2032 |
| C | HOH2091 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 1352 |
| Chain | Residue |
| D | PHE64 |
| D | SER65 |
| D | HIS125 |
| D | HOH2001 |
| site_id | EC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 1353 |
| Chain | Residue |
| D | THR70 |
| D | ALA121 |
| D | PHE122 |
| D | HIS125 |
| D | HOH2006 |
| D | HOH2044 |
| site_id | EC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO D 1354 |
| Chain | Residue |
| B | ASP111 |
| D | GLY273 |
| D | LYS283 |
| D | ASN330 |
| D | GLN332 |
| D | ASP333 |
| D | GLY345 |
| D | HOH2105 |
| D | HOH2127 |
| site_id | EC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 1355 |
| Chain | Residue |
| D | VAL217 |
| D | THR218 |
| D | LYS219 |
| D | GLU220 |
| site_id | EC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 1356 |
| Chain | Residue |
| D | ASN77 |
| D | SER79 |
| D | GLU83 |
| site_id | FC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO D 1357 |
| Chain | Residue |
| C | GLY156 |
| D | GLY148 |
| site_id | FC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 1358 |
| Chain | Residue |
| D | LEU144 |
| D | ILE149 |
| D | GLU150 |
| D | ASP152 |
| D | ARG158 |
| D | ILE159 |
| D | THR164 |
| site_id | FC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 1359 |
| Chain | Residue |
| D | LEU308 |
| D | GLU312 |
| D | GLU315 |
| site_id | FC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 1360 |
| Chain | Residue |
| D | LYS283 |
| D | SER285 |
| D | MET286 |
| D | EDO1361 |
| site_id | FC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 1361 |
| Chain | Residue |
| D | ASN277 |
| D | THR280 |
| D | GLU282 |
| D | EDO1360 |
| site_id | FC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 1362 |
| Chain | Residue |
| D | SER285 |
| D | GLY343 |
| D | ALA344 |
| D | GLY345 |
| D | MET347 |
| D | HOH2112 |
| D | HOH2134 |
| site_id | FC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 1363 |
| Chain | Residue |
| C | LYS227 |
| D | THR181 |
| D | GLN185 |
| D | HOH2135 |
| D | HOH2136 |
| site_id | FC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 1364 |
| Chain | Residue |
| D | LYS103 |
| D | ASP251 |
| D | HOH2027 |
| D | HOH2028 |
| D | HOH2030 |
| D | HOH2137 |
| site_id | FC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 1365 |
| Chain | Residue |
| D | SER95 |
| D | GLN98 |
| D | TYR129 |
| D | HOH2050 |
| site_id | GC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 1366 |
| Chain | Residue |
| D | THR67 |
| D | HIS125 |
| D | HOH2002 |
| D | HOH2004 |
| site_id | GC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 1367 |
| Chain | Residue |
| D | ASN270 |
| D | GLU271 |
| D | HOH2030 |
| D | HOH2106 |
| D | HOH2137 |
| site_id | GC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 1368 |
| Chain | Residue |
| C | SER195 |
| D | ARG169 |
| D | MET245 |
| site_id | GC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MLI D 1369 |
| Chain | Residue |
| D | ILE157 |
| D | GLY212 |
| D | VAL248 |
| D | ASN249 |
| D | NLG1370 |
| D | HOH2090 |
| D | HOH2139 |
| site_id | GC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE NLG D 1370 |
| Chain | Residue |
| D | GLY135 |
| D | THR136 |
| D | GLY137 |
| D | ARG158 |
| D | ASN247 |
| D | VAL248 |
| D | ASN249 |
| D | ALA250 |
| D | MLI1369 |
| D | HOH2027 |
| D | HOH2028 |
| D | HOH2058 |
| D | HOH2061 |
