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3ZYQ

Crystal structure of the tandem VHS and FYVE domains of Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS-Hrs) at 1.48 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATEpolymer22626047.91UniProt (O14964)
Pfam (PF00790)
Pfam (PF01363)
HOMO SAPIENS (HUMAN)HRS, PROTEIN PP110
2B, C
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
3D
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4E, F
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
5G
(A)
waterwater18.0155Chemie (HOH)
Sequence modifications
A: 1 - 225 (UniProt: O14964)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26047.9
Non-Polymers*Number of molecules5
Total formula weight351.0
All*Total formula weight26399.0
*Water molecules are not included.

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PDB entries from 2025-07-02

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