3ZWS
Structure of Human Dihydroorotate Dehydrogenase with a Bound Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL | polymer | 367 | 39856.5 | 1 | UniProt (Q02127) Pfam (PF01180) | HOMO SAPIENS (HUMAN) | DHODEHASE, DIHYDROOROTATE OXIDASE, DIHYDROOROTATE DEHYDROGENASE |
| 2 | B (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 3 | C (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 4 | D, E (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | G (A) | 2-[(2,5-DICHLOROBENZYL)SULFANYL]-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-OL | non-polymer | 341.2 | 1 | Chemie (AVQ) | |||
| 7 | H, I (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 8 | J (A) | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39856.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1299.3 | |
| All* | Total formula weight | 41155.9 |
