3ZVV
Fragment Bound to PI3Kinase gamma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | polymer | 966 | 110727.1 | 1 | UniProt (P48736) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) | HOMO SAPIENS (HUMAN) | PHOSPHOTIDYLINOSITOL 3 KINASE, PI3-KINASE SUBUNIT GAMMA, PI3K-GAMMA, PTDINS-3-KINASE SUBUNIT GAMMA, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE 110 KDA CATALYTIC SUBUNIT GAMMA, PTDINS-3-KINASE SUBUNIT P110-GAMMA, P120-PI3K |
| 2 | B (A) | 5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-amine | non-polymer | 162.2 | 1 | Chemie (XAZ) | |||
| 3 | C (A) | water | water | 18.0 | 287 | Chemie (HOH) |
Sequence modifications
A: 144 - 1102 (UniProt: P48736)
| PDB | External Database | Details |
|---|---|---|
| Met 143 | - | expression tag |
| His 1103 | - | expression tag |
| His 1104 | - | expression tag |
| His 1105 | - | expression tag |
| His 1106 | - | expression tag |
| His 1107 | - | expression tag |
| His 1108 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 110727.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 162.2 | |
| All* | Total formula weight | 110889.3 |
