3ZVV

Fragment Bound to PI3Kinase gamma

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM	polymer	966	110727.1	1	UniProt (P48736) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB	HOMO SAPIENS (HUMAN)	PHOSPHOTIDYLINOSITOL 3 KINASE, PI3-KINASE SUBUNIT GAMMA, PI3K-GAMMA, PTDINS-3-KINASE SUBUNIT GAMMA, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE 110 KDA CATALYTIC SUBUNIT GAMMA, PTDINS-3-KINASE SUBUNIT P110-GAMMA, P120-PI3K
2	A	5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-amine	non-polymer		162.2	1	Chemie (XAZ)
3		water	water		18.0	287	Chemie (HOH)

Sequence modifications

A: 144 - 1102 (UniProt: P48736)

PDB	External Database	Details
Met 143	-	expression tag
His 1103	-	expression tag
His 1104	-	expression tag
His 1105	-	expression tag
His 1106	-	expression tag
His 1107	-	expression tag
His 1108	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	110727.1
Non-Polymers*	Number of molecules	1
	Total formula weight	162.2
All*	Total formula weight	110889.3

*Water molecules are not included.