3ZVN
The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE | polymer | 416 | 45947.2 | 1 | UniProt (Q9JLV6) Pfam (PF08645) Pfam (PF13671) In PDB | Mus musculus (house mouse) | DNA 5'-KINASE/3'-PHOSPHATASE, POLYNUCLEOTIDE KINASE-3'-PHOSPHATASE, PNKP |
| 2 | E, F, G, H, I | 5'-D(*GP*TP*CP*AP*CP)-3' | polymer | 5 | 1480.0 | 5 | synthetic construct | ||
| 3 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 6 | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence modifications
A: 111 - 522 (UniProt: Q9JLV6)
| PDB | External Database | Details |
|---|---|---|
| Gly 107 | - | expression tag |
| Pro 108 | - | expression tag |
| His 109 | - | expression tag |
| Met 110 | - | expression tag |
| Asn 170 | Asp 170 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 53347.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 666.3 | |
| All* | Total formula weight | 54013.6 |
