3ZVM
The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE | polymer | 416 | 45932.2 | 2 | UniProt (Q9JLV6) Pfam (PF08645) Pfam (PF13671) In PDB | Mus musculus (house mouse) | DNA 5'-KINASE/3'-PHOSPHATASE, POLYNUCLEOTIDE KINASE-3'-PHOSPHATASE, PNKP |
2 | E, F | 5'-D(*GP*TP*CP*AP*CP)-3' | polymer | 5 | 1480.0 | 2 | synthetic construct | ||
3 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
4 | A, B | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
5 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
6 | A, B | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
7 | B | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
8 | water | water | 18.0 | 1196 | Chemie (HOH) |
Sequence modifications
A, B: 111 - 522 (UniProt: Q9JLV6)
PDB | External Database | Details |
---|---|---|
Gly 107 | - | expression tag |
Pro 108 | - | expression tag |
His 109 | - | expression tag |
Met 110 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 94824.5 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 2283.1 | |
All* | Total formula weight | 97107.6 |