3ZVM
The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE | polymer | 416 | 45932.2 | 2 | UniProt (Q9JLV6) Pfam (PF08645) Pfam (PF13671) | Mus musculus (house mouse) | DNA 5'-KINASE/3'-PHOSPHATASE, POLYNUCLEOTIDE KINASE-3'-PHOSPHATASE, PNKP |
| 2 | C, D (E, F) | 5'-D(*GP*TP*CP*AP*CP)-3' | polymer | 5 | 1480.0 | 2 | synthetic construct | ||
| 3 | E, M (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | F, N (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 5 | G, H, O, P (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | I, J, K, L, Q... (A, B) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 7 | U, V (B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 8 | W, X, Y, Z (A, B, E, F) | water | water | 18.0 | 1196 | Chemie (HOH) |
Sequence modifications
A, B: 111 - 522 (UniProt: Q9JLV6)
| PDB | External Database | Details |
|---|---|---|
| Gly 107 | - | expression tag |
| Pro 108 | - | expression tag |
| His 109 | - | expression tag |
| Met 110 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 94824.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2283.1 | |
| All* | Total formula weight | 97107.6 |
