3ZUK
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ZINC METALLOPROTEASE ZMP1 IN COMPLEX WITH INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ENDOPEPTIDASE, PEPTIDASE FAMILY M13 | polymer | 699 | 78133.0 | 2 | UniProt (O53649) Pfam (PF05649) Pfam (PF01431) | MYCOBACTERIUM TUBERCULOSIS | PROBABLE ZINC METALLOPROTEASE, ZMP1 METALLOPROTEASE |
| 2 | C, IA (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, JA (A, B) | N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN | non-polymer | 543.5 | 2 | BIRD (PRD_000638) Chemie (RDF) | |||
| 4 | E (A) | 2,2',2''-NITRILOTRIETHANOL | non-polymer | 149.2 | 1 | Chemie (211) | |||
| 5 | F, G, H, I, J... (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 30 | Chemie (PEG) | |||
| 6 | AB, BB, U, V, W... (B, A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 8 | Chemie (PGE) | |||
| 7 | CB, DB, EB, Z (B, A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 4 | Chemie (PG4) | |||
| 8 | AA, BA, CA, DA, EA... (A, B) | ACETATE ION | non-polymer | 59.0 | 13 | Chemie (ACT) | |||
| 9 | FA, GA, NB, OB, PB... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 10 | HA, RB, TB (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 11 | SB (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 12 | UB, VB (A, B) | water | water | 18.0 | 332 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 663 (UniProt: O53649)
| PDB | External Database | Details |
|---|---|---|
| Met -35 | - | expression tag |
| Arg -34 | - | expression tag |
| Gly -33 | - | expression tag |
| Ser -32 | - | expression tag |
| His -31 | - | expression tag |
| His -30 | - | expression tag |
| His -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Met -24 | - | expression tag |
| Ala -23 | - | expression tag |
| Ser -22 | - | expression tag |
| Met -21 | - | expression tag |
| Thr -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Gln -17 | - | expression tag |
| Gln -16 | - | expression tag |
| Met -15 | - | expression tag |
| Gly -14 | - | expression tag |
| Arg -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Leu -11 | - | expression tag |
| Tyr -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Asp -4 | - | expression tag |
| His -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 156265.9 | |
| Non-Polymers* | Number of molecules | 70 |
| Total formula weight | 8019.3 | |
| All* | Total formula weight | 164285.2 |
