Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016485 | biological_process | protein processing |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0016485 | biological_process | protein processing |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1664 |
| Chain | Residue |
| A | HIS493 |
| A | HIS497 |
| A | GLU560 |
| A | RDF1665 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1664 |
| Chain | Residue |
| B | HIS493 |
| B | HIS497 |
| B | GLU560 |
| B | RDF1665 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE RDF B 1665 |
| Chain | Residue |
| B | ASN452 |
| B | ALA453 |
| B | TYR454 |
| B | ILE468 |
| B | HIS493 |
| B | GLU494 |
| B | HIS497 |
| B | GLU560 |
| B | HIS622 |
| B | ARG628 |
| B | ZN1664 |
| B | ACT1691 |
| B | HOH2071 |
| B | HOH2171 |
| B | PHE48 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE RDF A 1665 |
| Chain | Residue |
| A | PHE48 |
| A | VAL451 |
| A | ASN452 |
| A | ALA453 |
| A | TYR454 |
| A | HIS493 |
| A | GLU494 |
| A | HIS497 |
| A | GLU560 |
| A | ARG616 |
| A | HIS622 |
| A | ARG628 |
| A | ZN1664 |
| A | 2111666 |
| A | PGE1684 |
| A | ACT1689 |
| A | HOH2148 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 211 A 1666 |
| Chain | Residue |
| A | ARG615 |
| A | ARG616 |
| A | ASP620 |
| A | RDF1665 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG B 1666 |
| Chain | Residue |
| B | ARG126 |
| B | THR248 |
| B | ALA249 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 1667 |
| Chain | Residue |
| A | PRO6 |
| A | SER7 |
| A | GLY8 |
| A | ASP10 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG B 1667 |
| Chain | Residue |
| B | GLN153 |
| B | SER154 |
| B | GLY155 |
| B | ILE156 |
| B | ARG219 |
| B | HOH2051 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 1668 |
| Chain | Residue |
| A | PHE52 |
| A | VAL329 |
| A | GLU333 |
| A | GLN449 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG B 1668 |
| Chain | Residue |
| B | SER162 |
| B | ASP166 |
| B | HIS169 |
| B | ILE614 |
| B | LEU617 |
| B | ALA618 |
| B | HOH2140 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG A 1669 |
| Chain | Residue |
| A | SER86 |
| A | PRO100 |
| A | TRP298 |
| A | ASP414 |
| A | ASP415 |
| A | LEU416 |
| A | TYR417 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 1670 |
| Chain | Residue |
| A | ALA77 |
| A | HOH2019 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 1671 |
| Chain | Residue |
| A | ASN227 |
| A | LEU228 |
| A | ARG229 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG A 1672 |
| Chain | Residue |
| A | GLN641 |
| A | ASP644 |
| A | VAL645 |
| A | PGE1683 |
| B | GLN576 |
| B | LEU577 |
| B | ASN580 |
| B | GLY581 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG B 1669 |
| Chain | Residue |
| B | GLN576 |
| B | ALA638 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG B 1670 |
| Chain | Residue |
| A | GLN534 |
| A | ARG634 |
| A | ARG657 |
| A | PEG1679 |
| B | ASP545 |
| B | PRO547 |
| B | GLY548 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG B 1671 |
| Chain | Residue |
| B | ALA127 |
| B | ALA425 |
| B | THR123 |
| B | ARG126 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PEG B 1672 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 1673 |
| Chain | Residue |
| A | ASP479 |
| A | GLU480 |
| A | HOH2117 |
| A | HOH2139 |
| B | ILE5 |
| B | ASP479 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG B 1673 |
| Chain | Residue |
| B | ASP138 |
| B | THR139 |
| B | SER141 |
| B | ASN456 |
| B | PRO457 |
| B | GLY458 |
| B | TYR506 |
| site_id | CC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PEG A 1674 |
| site_id | CC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG B 1674 |
| Chain | Residue |
| B | LYS354 |
| B | ASP358 |
| B | ALA395 |
| B | LYS396 |
| B | VAL397 |
| B | TYR399 |
| B | ILE401 |
| B | TRP444 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 1675 |
| Chain | Residue |
| A | THR152 |
| A | ARG219 |
| A | ARG263 |
| site_id | CC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG A 1676 |
| Chain | Residue |
| A | ALA613 |
| A | ARG616 |
| A | LEU617 |
| A | ASP620 |
| A | HIS622 |
| A | SER623 |
| A | PRO624 |
| A | PRO625 |
| A | HOH2147 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 1677 |
| Chain | Residue |
| A | ASP358 |
| A | ASP362 |
| A | ALA395 |
| site_id | CC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG A 1678 |
| Chain | Residue |
| A | ASP17 |
| A | ALA18 |
| A | ARG19 |
| A | ASP22 |
| A | ASP23 |
| A | PEG1680 |
| A | ACT1688 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG B 1675 |
| Chain | Residue |
| A | ASN582 |
| B | ALA4 |
| B | SER7 |
| B | ASP588 |
| site_id | DC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG B 1676 |
| Chain | Residue |
| A | VAL544 |
| A | ASP545 |
| B | ASP22 |
| B | ARG541 |
| B | GLU626 |
| B | PHE627 |
| B | ASN630 |
| B | LEU651 |
| site_id | DC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 1679 |
| Chain | Residue |
| A | GLU533 |
| A | GLN534 |
| A | ARG657 |
| B | PEG1670 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG B 1677 |
| Chain | Residue |
| B | VAL216 |
| B | ARG220 |
| B | ACT1694 |
| B | SO41697 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 1678 |
| Chain | Residue |
| B | LYS392 |
| B | ASP507 |
| B | GLY508 |
| B | VAL513 |
| B | HOH2105 |
| site_id | DC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 1680 |
| Chain | Residue |
| A | ASP22 |
| A | PEG1678 |
| B | ASP545 |
| site_id | DC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG B 1679 |
| Chain | Residue |
| A | GLU116 |
| B | ASN227 |
| B | ARG229 |
| site_id | DC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 1681 |
| Chain | Residue |
| A | ASN363 |
| A | ALA574 |
| A | LEU577 |
| A | ASN580 |
| site_id | DC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG B 1680 |
| Chain | Residue |
| B | PHE349 |
| B | ALA353 |
| B | LYS354 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE B 1681 |
| Chain | Residue |
| A | ASN580 |
| B | HIS27 |
| B | GLY589 |
| B | GLN594 |
| B | PG41685 |
| B | PG41685 |
| site_id | EC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE A 1682 |
| Chain | Residue |
| A | GLU374 |
| A | LEU573 |
| B | ASP637 |
| B | ARG658 |
| B | HOH2161 |
| B | HOH2163 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE B 1682 |
| Chain | Residue |
| B | ASP221 |
| B | ASP501 |
| B | LYS505 |
| B | ASP514 |
| B | TRP516 |
| site_id | EC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PGE A 1683 |
| Chain | Residue |
| A | ASP637 |
| A | GLN641 |
| A | ARG658 |
| A | PEG1672 |
| site_id | EC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PGE A 1684 |
| Chain | Residue |
| A | TYR454 |
| A | TYR455 |
| A | HIS497 |
| A | RDF1665 |
| site_id | EC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PGE B 1683 |
| Chain | Residue |
| A | LEU579 |
| A | ALA584 |
| A | HOH2144 |
| B | LEU579 |
| B | ALA584 |
| B | ACT1687 |
| B | HOH2150 |
| site_id | EC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PGE A 1685 |
| Chain | Residue |
| A | GLN319 |
| A | LYS607 |
| A | ARG609 |
| B | ASP648 |
| site_id | EC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE A 1686 |
| Chain | Residue |
| A | ALA16 |
| A | HIS27 |
| A | ASP588 |
| A | GLY589 |
| A | GLN594 |
| A | HOH2006 |
| site_id | EC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PG4 B 1684 |
| Chain | Residue |
| B | PRO540 |
| B | ASP542 |
| B | GLN553 |
| B | THR557 |
| B | ALA613 |
| B | ARG616 |
| B | LEU617 |
| B | ASP620 |
| B | HIS622 |
| B | PRO624 |
| B | GLU626 |
| B | HOH2153 |
| site_id | EC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1687 |
| Chain | Residue |
| A | HIS13 |
| A | TRP32 |
| A | GLU35 |
| A | HIS36 |
| A | ASP45 |
| A | SER50 |
| site_id | FC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PG4 B 1685 |
| Chain | Residue |
| B | LEU11 |
| B | ALA16 |
| B | ARG19 |
| B | HIS27 |
| B | PGE1681 |
| B | PGE1681 |
| B | HOH2010 |
| B | HOH2149 |
| site_id | FC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PG4 B 1686 |
| Chain | Residue |
| A | VAL544 |
| A | ASP545 |
| A | HIS546 |
| A | HOH2133 |
| B | GLN534 |
| B | TYR538 |
| B | ARG634 |
| B | ARG657 |
| site_id | FC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 1687 |
| Chain | Residue |
| A | GLY581 |
| B | THR591 |
| B | MET593 |
| B | PGE1683 |
| B | HOH2150 |
| B | HOH2173 |
| site_id | FC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 1688 |
| Chain | Residue |
| A | ASP15 |
| A | GLY30 |
| A | ARG541 |
| A | PEG1678 |
| site_id | FC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 1688 |
| Chain | Residue |
| B | TYR147 |
| B | ALA256 |
| B | MET257 |
| B | THR258 |
| site_id | FC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1689 |
| Chain | Residue |
| A | PHE445 |
| A | RDF1665 |
| site_id | FC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT B 1689 |
| site_id | FC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ACT B 1690 |
| site_id | FC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 1691 |
| Chain | Residue |
| B | TYR455 |
| B | HIS497 |
| B | RDF1665 |
| B | ACT1694 |
| site_id | GC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 1692 |
| Chain | Residue |
| B | GLN125 |
| B | GLY134 |
| B | VAL135 |
| site_id | GC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 1693 |
| Chain | Residue |
| A | ACT1691 |
| B | ASP479 |
| B | TYR575 |
| B | LEU579 |
| B | PRO585 |
| site_id | GC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1690 |
| Chain | Residue |
| A | TRP516 |
| A | ARG521 |
| site_id | GC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 1691 |
| Chain | Residue |
| A | ILE5 |
| B | ASN582 |
| B | ACT1693 |
| site_id | GC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 1694 |
| Chain | Residue |
| B | HIS497 |
| B | PEG1677 |
| B | ACT1691 |
| B | HOH2073 |
| site_id | GC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 1692 |
| Chain | Residue |
| A | GLN125 |
| A | VAL129 |
| A | VAL135 |
| site_id | GC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1695 |
| Chain | Residue |
| A | LEU577 |
| A | ASN580 |
| B | ASP644 |
| B | VAL645 |
| B | HOH2163 |
| site_id | GC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1693 |
| Chain | Residue |
| A | HIS536 |
| A | HIS551 |
| A | VAL552 |
| A | GLN553 |
| A | GLY554 |
| A | ALA555 |
| A | HOH2159 |
| site_id | GC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1696 |
| Chain | Residue |
| B | ILE532 |
| B | HIS536 |
| B | GLN553 |
| B | GLY554 |
| B | ALA555 |
| site_id | HC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1697 |
| Chain | Residue |
| B | THR152 |
| B | ARG219 |
| B | ARG263 |
| B | PEG1677 |
| B | HOH2045 |
| site_id | HC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1694 |
| Chain | Residue |
| A | ARG42 |
| A | ALA43 |
| A | ARG49 |
| A | HOH2086 |
| site_id | HC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1698 |
| Chain | Residue |
| B | ARG42 |
| B | ALA43 |
| B | THR44 |
| B | ARG49 |
| site_id | HC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1699 |
| Chain | Residue |
| B | ASP242 |
| B | ILE411 |
| site_id | HC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1695 |
| Chain | Residue |
| A | TYR147 |
| A | LEU435 |
| site_id | HC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 1700 |
| Chain | Residue |
| B | ASP113 |
| B | GLU116 |
| B | ASP412 |
| B | ASP414 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VIGHEIGHGF |
| Chain | Residue | Details |
| A | VAL490-PHE499 | |
