3ZRC

pVHL54-213-EloB-EloC complex (4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J	TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2	polymer	118	13147.8	4	UniProt (Q15370) Pfam (PF00240) In PDB	HOMO SAPIENS	ELONGIN 18 KDA SUBUNIT, ELONGIN-B, ELOB, RNA POLYMERASE II TRANSCRIPTION FACTOR SIII SUBUNIT B, SIII P18, ELONGINB
2	B, E, H, K	TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1	polymer	97	10974.6	4	UniProt (Q15369) Pfam (PF03931) In PDB	HOMO SAPIENS	ELONGIN 15 KDA SUBUNIT, ELONGIN-C, ELOC, RNA POLYMERASE II TRANSCRIPTION FACTOR SIII SUBUNIT C, SIII P15, ELONGINC
3	C, F, I, L	VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR	polymer	163	18840.4	4	UniProt (P40337) Pfam (PF01847) Pfam (PF17211) In PDB	HOMO SAPIENS	PROTEIN G7, PVHL
4	C, F, I, L	(4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE	non-polymer		410.4	4	Chemie (L8B)
5		water	water		18.0	10	Chemie (HOH)

Sequence modifications

B, E, H, K: 17 - 112 (UniProt: Q15369)

PDB	External Database	Details
Met 16	-	expression tag

C, F, I, L: 54 - 213 (UniProt: P40337)

PDB	External Database	Details
Gly 51	-	expression tag
Ser 52	-	expression tag
His 53	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	171851.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1641.7
All*	Total formula weight	173493.0

*Water molecules are not included.