3ZM3
Catalytic domain of human SHP2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 | polymer | 284 | 33163.7 | 1 | UniProt (Q06124) Pfam (PF00102) | HOMO SAPIENS (HUMAN) | PROTEIN-TYROSINE PHOSPHATASE 1D, PTP-1D, PROTEIN-TYROSINE PHOSPHATASE 2C, PTP-2C, SH-PTP2, SHP-2, SHP2, SH-PTP3 |
| 2 | B (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 248 - 527 (UniProt: Q06124)
| PDB | External Database | Details |
|---|---|---|
| Gly 244 | - | expression tag |
| Ala 245 | - | expression tag |
| His 246 | - | expression tag |
| Met 247 | - | expression tag |
| - | Gln 408 | deletion |
| - | Ala 409 | deletion |
| - | Leu 410 | deletion |
| - | Leu 411 | deletion |
| Arg 486 | Cys 490 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33163.7 | |
| All* | Total formula weight | 33163.7 |
