3ZLN
Crystal structure of BCL-XL in complex with inhibitor (Compound 3)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | BCL-2-LIKE PROTEIN 1 | polymer | 181 | 20804.9 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | HOMO SAPIENS (HUMAN) | BCL2-L-1, APOPTOSIS REGULATOR BCL-X, BCL-XL |
| 2 | A | 6-[(8E)-8-(1,3-benzothiazol-2-ylhydrazinylidene)-6,7-dihydro-5H-naphthalen-2-yl]pyridine-2-carboxylic acid | non-polymer | 414.5 | 1 | Chemie (H0Y) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 1 - 44 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| Met -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Met -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Leu 210 | - | expression tag |
| Glu 211 | - | expression tag |
| His 212 | - | expression tag |
| His 213 | - | expression tag |
| His 214 | - | expression tag |
| His 215 | - | expression tag |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20804.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 820.9 | |
| All* | Total formula weight | 21625.8 |
