3ZKS
BACE2 XAPERONE COMPLEX WITH INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BETA-SECRETASE 2 | polymer | 386 | 42105.4 | 1 | UniProt (Q9Y5Z0) Pfam (PF00026) | HOMO SAPIENS (HUMAN) | ASPARTIC-LIKE PROTEASE 56 KDA, ASPARTYL PROTEASE 1, ASP1, ASP 1, BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 2, BETA- SITE APP CLEAVING ENZYME 2, DOWN REGION ASPARTIC PROTEASE, DRAP, MEMAPSIN-1, MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 1, THETA-SECRETASE, BACE2 |
| 2 | B (D) | XA4813 | polymer | 122 | 13152.5 | 1 | LAMA GLAMA (LLAMA) | ||
| 3 | C (A) | 5-(2,2,2-Trifluoro-ethoxy)-pyridine-2-carboxylic acid [3-((S)-2-amino-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-4-yl)-phenyl]-amide | non-polymer | 435.4 | 1 | Chemie (WZV) | |||
| 4 | D, E (A, D) | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55257.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 435.4 | |
| All* | Total formula weight | 55693.3 |
