3ZKP
Structure of a mutant of P450 EryK in complex with erythromycin B.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ERYTHROMYCIN C-12 HYDROXYLASE | polymer | 411 | 45286.9 | 1 | UniProt (P48635) Pfam (PF00067) | SACCHAROPOLYSPORA ERYTHRAEA NRRL 2338 | CYTOCHROME P450 113A1, ERYK, CYP113A1, ERYTHROMYCIN D C-12 HYDROXYLASE |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | Erythromycin B | non-polymer | 717.9 | 1 | Chemie (ERB) PubChem (23376603) PubChem (177425424) PubChem (44335751) PubChem (59511084) PubChem (60044165) PubChem (176507482) PubChem (10702) PubChem (594168) PubChem (9918244) PubChem (141646829) PubChem (162951377) PubChem (163640348) PubChem (169289156) PubChem (175673191) PubChem (129692509) PubChem (131880311) PubChem (133562679) PubChem (171036598) | |||
| 4 | D (A) | water | water | 18.0 | 329 | Chemie (HOH) |
Sequence modifications
A: 16 - 411 (UniProt: P48635)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | SEE REMARK 999 |
| Phe 2 | - | SEE REMARK 999 |
| Ala 3 | - | SEE REMARK 999 |
| Asp 4 | - | SEE REMARK 999 |
| Val 5 | - | SEE REMARK 999 |
| Glu 6 | - | SEE REMARK 999 |
| Thr 7 | - | SEE REMARK 999 |
| Thr 8 | - | SEE REMARK 999 |
| Cys 9 | - | SEE REMARK 999 |
| Cys 10 | - | SEE REMARK 999 |
| Ala 11 | - | SEE REMARK 999 |
| Arg 12 | - | SEE REMARK 999 |
| Arg 13 | - | SEE REMARK 999 |
| Thr 14 | - | SEE REMARK 999 |
| Leu 15 | - | SEE REMARK 999 |
| Ala 86 | Met 72 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45286.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1334.4 | |
| All* | Total formula weight | 46621.3 |
