Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0020037 | molecular_function | heme binding |
| A | 0033068 | biological_process | macrolide biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM A 412 |
| Chain | Residue |
| A | ILE87 |
| A | THR246 |
| A | LEU249 |
| A | MET291 |
| A | ARG293 |
| A | SER345 |
| A | PHE346 |
| A | GLY347 |
| A | HIS351 |
| A | CYS353 |
| A | GLY355 |
| A | HIS88 |
| A | ALA359 |
| A | ERB413 |
| A | HOH2067 |
| A | HOH2213 |
| A | HOH2289 |
| A | HOH2328 |
| A | HIS95 |
| A | ARG99 |
| A | PHE106 |
| A | LEU238 |
| A | ALA241 |
| A | GLY242 |
| A | THR245 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ERB A 413 |
| Chain | Residue |
| A | HIS88 |
| A | GLU89 |
| A | PRO177 |
| A | ILE186 |
| A | LEU190 |
| A | ALA237 |
| A | LEU240 |
| A | ALA241 |
| A | THR245 |
| A | PHE288 |
| A | GLN292 |
| A | HEM412 |
| A | HOH2086 |
| A | HOH2212 |
| A | HOH2213 |
| A | HOH2248 |
| A | HOH2254 |
| A | HOH2329 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGhGVHFCLG |
| Chain | Residue | Details |
| A | PHE346-GLY355 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 19 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"axial binding residue"} |
