3ZK6

Crystal structure of Bcl-xL in complex with inhibitor (Compound 2).

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	BCL-2-LIKE PROTEIN 1	polymer	181	20771.1	2	UniProt (Q07817) Pfam (PF02180) Pfam (PF00452)	HOMO SAPIENS (HUMAN)	BCL2-L-1, APOPTOSIS REGULATOR BCL-X, BCL-XL
2	C, D (A, B)	N-(3-(5-(1-(2-(benzo[d]thiazol-2-yl)hydrazono)ethyl)furan-2-yl)phenylsulfonyl)-6-phenylhexanamide	non-polymer		586.7	2	Chemie (H1I)
3	E, F (A, B)	water	water		18.0	54	Chemie (HOH)

Sequence modifications

A, B: 1 - 40 (UniProt: Q07817)

PDB	External Database	Details
Met -3	-	expression tag
Ser -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag
Leu 210	-	expression tag
Glu 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	41542.1
Non-Polymers*	Number of molecules	2
	Total formula weight	1173.4
All*	Total formula weight	42715.6

*Water molecules are not included.