3ZHA

Molecular basis for the action of the collagen-specific chaperone Hsp47 SERPINH1 and its structure-specific client recognition.

Replaces:  4AWR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, K... (A, B, C, D, K...)	HSP47	polymer	392	44283.7	8	UniProt (C7C419) Pfam (PF00079)	CANIS LUPUS FAMILIARIS (DOG)	SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), MEMBER 1, COLLAGEN BINDING PROTEIN 1
2	E, F, G, H, I... (E, F, G, H, I...)	COLLAGEN MODEL PEPTIDE 18-T8R11	polymer	19	1556.8	12		SYNTHETIC CONSTRUCT
3	U, V, W, X, Y (A, C, K, P, Q)	SUCCINIC ACID	non-polymer		118.1	5	Chemie (SIN)
4	AA, BA, CA, DA, EA... (B, C, D, E, F...)	water	water		18.0	222	Chemie (HOH)

Sequence modifications

A, B, C, D, K, L, P, Q: 36 - 418 (UniProt: C7C419)

PDB	External Database	Details
Met 35	-	expression tag
Leu 419	-	expression tag
Glu 420	-	expression tag
His 421	-	expression tag
His 422	-	expression tag
His 423	-	expression tag
His 424	-	expression tag
His 425	-	expression tag
His 426	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	20
	Total formula weight	372950.6
Non-Polymers*	Number of molecules	5
	Total formula weight	590.4
All*	Total formula weight	373541.1

*Water molecules are not included.