3ZGO
Re-refined structure of the human Sirt2 apoform
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2 | polymer | 325 | 36660.1 | 3 | UniProt (Q8IXJ6) Pfam (PF02146) | HOMO SAPIENS (HUMAN) | SIRTUIN 2, ISOFORM 1, REGULATORY PROTEIN SIR2 HOMOLOG 2, SIR2-LIKE PROTEIN 2 |
| 2 | D, H, K (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E (A) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 4 | F, I, L, M, N... (A, B, C) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 7 | Chemie (PGE) | |||
| 5 | G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | J (B) | ETHANOL | non-polymer | 46.1 | 1 | Chemie (EOH) | |||
| 7 | Q, R, S (A, B, C) | water | water | 18.0 | 1082 | Chemie (HOH) |
Sequence modifications
A, B, C: 34 - 356 (UniProt: Q8IXJ6)
| PDB | External Database | Details |
|---|---|---|
| Gly 32 | - | expression tag |
| Ser 33 | - | expression tag |
| Pro 239 | Leu 239 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 109980.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1637.9 | |
| All* | Total formula weight | 111618.3 |
