3WZU

THE STRUCTURE OF MAP2K7 IN COMPLEX WITH 5Z-7-oxozeaenol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Dual specificity mitogen-activated protein kinase kinase 7	polymer	324	36998.9	1	UniProt (O14733) Pfam (PF00069) In PDB	Homo sapiens (human)	MAP kinase kinase 7, MAPKK 7, JNK-activating kinase 2, MAPK/ERK kinase 7, MEK 7, Stress-activated protein kinase kinase 4, SAPK kinase 4, SAPKK-4, SAPKK4, c-Jun N-terminal kinase kinase 2, JNK kinase 2, JNKK 2
2	A	(3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione	non-polymer		362.4	1	Chemie (1FM)
3		water	water		18.0	24	Chemie (HOH)

Sequence modifications

A: 119 - 435 (UniProt: O14733)

PDB	External Database	Details
Met 118	-	expression tag
His 436	-	expression tag
His 437	-	expression tag
His 438	-	expression tag
His 439	-	expression tag
His 440	-	expression tag
His 441	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36998.9
Non-Polymers*	Number of molecules	1
	Total formula weight	362.4
All*	Total formula weight	37361.3

*Water molecules are not included.