3WQS
Crystal structure of pfdxr complexed with inhibitor-126
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplast | polymer | 488 | 55829.6 | 1 | UniProt (O96693) Pfam (PF02670) Pfam (PF08436) Pfam (PF13288) | Plasmodium falciparum | 1-deoxyxylulose-5-phosphate reductoisomerase, DOXP reductoisomerase, DXP reductoisomerase |
| 2 | B (B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 3 | C (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (B) | [(R)-{2-[hydroxy(methyl)amino]-2-oxoethoxy}(4-methoxyphenyl)methyl]phosphonic acid | non-polymer | 305.2 | 1 | Chemie (KBK) | |||
| 5 | E (B) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55829.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1074.9 | |
| All* | Total formula weight | 56904.6 |
