3WNX
Crystal structure of ERGIC-53/MCFD2, Calcium/Man3-bound form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein ERGIC-53 | polymer | 246 | 27154.2 | 1 | UniProt (P49257) Pfam (PF03388) | Homo sapiens (human) | ER-Golgi intermediate compartment 53 kDa protein, Gp58, Intracellular mannose-specific lectin MR60, Lectin mannose-binding 1 |
| 2 | B (B) | Multiple coagulation factor deficiency protein 2 | polymer | 104 | 12056.2 | 1 | UniProt (Q8NI22) Pfam (PF13499) | Homo sapiens (human) | MCFD2, Neural stem cell-derived neuronal survival protein |
| 3 | C (C) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900111) GlyTouCan (G53402KW) | 2alpha-alpha-mannobiose | ||
| 4 | D, E, F, G (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | H (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 31 - 269 (UniProt: P49257)
B: 67 - 146 (UniProt: Q8NI22)
| PDB | External Database | Details |
|---|---|---|
| Met 24 | - | expression tag |
| Asn 25 | - | expression tag |
| His 26 | - | expression tag |
| Lys 27 | - | expression tag |
| Val 28 | - | expression tag |
| His 29 | - | expression tag |
| Met 30 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 43 | - | expression tag |
| Gly 44 | - | expression tag |
| His 45 | - | expression tag |
| His 46 | - | expression tag |
| His 47 | - | expression tag |
| His 48 | - | expression tag |
| His 49 | - | expression tag |
| His 50 | - | expression tag |
| His 51 | - | expression tag |
| His 52 | - | expression tag |
| His 53 | - | expression tag |
| His 54 | - | expression tag |
| Ser 55 | - | expression tag |
| Ser 56 | - | expression tag |
| Gly 57 | - | expression tag |
| His 58 | - | expression tag |
| Ile 59 | - | expression tag |
| Glu 60 | - | expression tag |
| Gly 61 | - | expression tag |
| Arg 62 | - | expression tag |
| His 63 | - | expression tag |
| Met 64 | - | expression tag |
| Leu 65 | - | expression tag |
| Glu 66 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39210.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 39713.0 |
