3WKT
Complex structure of an open form of NADPH-cytochrome P450 reductase and heme oxygenase-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NADPH-cytochrome P450 reductase | polymer | 618 | 70282.1 | 2 | UniProt (P00388) Pfam (PF00258) Pfam (PF00667) Pfam (PF00175) | Rattus norvegicus (brown rat rat rats) | CPR, P450R |
| 2 | C, D (C, D) | Heme oxygenase 1 | polymer | 267 | 30612.5 | 2 | UniProt (P06762) Pfam (PF01126) | Rattus norvegicus (brown rat rat rats) | HO-1, HSP32 |
| 3 | E, H (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 4 | F, I (A, B) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 2 | Chemie (FMN) PubChem (23585816) PubChem (51435500) PubChem (51435503) PubChem (710) PubChem (15559251) PubChem (8965) PubChem (643976) PubChem (5702760) PubChem (7048779) PubChem (7048781) | |||
| 5 | G, J (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) PubChem (46936685) PubChem (71717786) PubChem (165382010) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (5885) PubChem (174001641) | |||
| 6 | K, L (C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) |
Sequence modifications
A, B: 58 - 674 (UniProt: P00388)
| PDB | External Database | Details |
|---|---|---|
| Met 57 | - | expression tag |
| - | Thr 236 | deletion |
| - | Gly 237 | deletion |
| - | Glu 238 | deletion |
| - | Glu 239 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 201789.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 5203.6 | |
| All* | Total formula weight | 206992.8 |
