3WIZ

Crystal structure of Bcl-xL in complex with compound 10

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Bcl-2-like protein 1	polymer	177	20384.4	2	UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB	Homo sapiens (human)	Bcl2-L-1, Apoptosis regulator Bcl-X
2	A, B	7-(4-{[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrophenyl)sulfonyl]carbamoyl}-2-methylphenyl)-3-[3-(naphthalen-1-yloxy)propyl]pyrazolo[1,5-a]pyridine-2-carboxylic acid	non-polymer		887.0	2	Chemie (LC6)
3	A, B	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4		water	water		18.0	17	Chemie (HOH)

Sequence modifications

A, B: 1 - 44 (UniProt: Q07817)
A, B: 85 - 209 (UniProt: Q07817)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40768.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1964.0
All*	Total formula weight	42732.7

*Water molecules are not included.