Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0042981 | biological_process | regulation of apoptotic process |
B | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE LC6 A 501 |
Chain | Residue |
A | GLU96 |
A | ARG139 |
A | VAL141 |
B | TYR195 |
A | PHE97 |
A | ARG100 |
A | TYR101 |
A | GLU129 |
A | LEU130 |
A | ASN136 |
A | TRP137 |
A | GLY138 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE PO4 A 502 |
Chain | Residue |
A | TYR120 |
A | TYR120 |
A | TYR120 |
A | GLN121 |
A | GLN121 |
A | GLN121 |
site_id | AC3 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE LC6 B 501 |
Chain | Residue |
A | TYR195 |
B | GLU96 |
B | PHE97 |
B | ARG100 |
B | TYR101 |
B | PHE105 |
B | ASN136 |
B | TRP137 |
B | GLY138 |
B | ARG139 |
B | VAL141 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE PO4 B 502 |
Chain | Residue |
B | TYR120 |
B | TYR120 |
B | TYR120 |
B | GLN121 |
B | GLN121 |
B | GLN121 |
Functional Information from PROSITE/UniProt
site_id | PS01080 |
Number of Residues | 19 |
Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG |
Chain | Residue | Details |
A | LEU130-GLY148 | |
site_id | PS01258 |
Number of Residues | 12 |
Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV |
Chain | Residue | Details |
A | TRP181-VAL192 | |
site_id | PS01259 |
Number of Residues | 15 |
Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR |
Chain | Residue | Details |
A | VAL86-ARG100 | |
site_id | PS01260 |
Number of Residues | 21 |
Details | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW |
Chain | Residue | Details |
A | SER4-TRP24 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | SITE: Cleavage; by caspase-1 |
Chain | Residue | Details |
A | TYR101 | |
B | TYR101 | |
Chain | Residue | Details |
A | ALA89 | |
B | ALA89 | |
Chain | Residue | Details |
A | ARG102 | |
B | ARG102 | |