3WCE
The complex structure of TcSQS with ligand, ER119884
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Farnesyltransferase, putative | polymer | 365 | 41861.8 | 4 | UniProt (Q4CWB4) Pfam (PF00494) In PDB | Trypanosoma cruzi | |
2 | A, B, C, D | (3R)-3-{[2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl]ethynyl}-1-azabicyclo[2.2.2]octan-3-ol | non-polymer | 406.5 | 4 | Chemie (ER4) | |||
3 | water | water | 18.0 | 347 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 25 - 368 (UniProt: Q4CWB4)
PDB | External Database | Details |
---|---|---|
Met 4 | - | expression tag |
Gly 5 | - | expression tag |
Ser 6 | - | expression tag |
Ser 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
His 12 | - | expression tag |
His 13 | - | expression tag |
Ser 14 | - | expression tag |
Ser 15 | - | expression tag |
Gly 16 | - | expression tag |
Leu 17 | - | expression tag |
Val 18 | - | expression tag |
Pro 19 | - | expression tag |
Arg 20 | - | expression tag |
Gly 21 | - | expression tag |
Ser 22 | - | expression tag |
His 23 | - | expression tag |
Met 24 | - | expression tag |
Glu 82 | Asp 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 167447.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1626.1 | |
All* | Total formula weight | 169073.3 |