3WCE
The complex structure of TcSQS with ligand, ER119884
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004310 | molecular_function | farnesyl-diphosphate farnesyltransferase activity |
| A | 0004311 | molecular_function | farnesyltranstransferase activity |
| A | 0008610 | biological_process | lipid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0004310 | molecular_function | farnesyl-diphosphate farnesyltransferase activity |
| B | 0004311 | molecular_function | farnesyltranstransferase activity |
| B | 0008610 | biological_process | lipid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0004310 | molecular_function | farnesyl-diphosphate farnesyltransferase activity |
| C | 0004311 | molecular_function | farnesyltranstransferase activity |
| C | 0008610 | biological_process | lipid biosynthetic process |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0004310 | molecular_function | farnesyl-diphosphate farnesyltransferase activity |
| D | 0004311 | molecular_function | farnesyltranstransferase activity |
| D | 0008610 | biological_process | lipid biosynthetic process |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ER4 A 401 |
| Chain | Residue |
| A | PHE45 |
| A | MET199 |
| A | GLY200 |
| A | TYR270 |
| A | TYR64 |
| A | LEU67 |
| A | ARG68 |
| A | ASP71 |
| A | ALA168 |
| A | VAL171 |
| A | GLY172 |
| A | LEU175 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ER4 B 401 |
| Chain | Residue |
| B | PHE45 |
| B | TYR64 |
| B | ARG68 |
| B | ASP71 |
| B | ALA168 |
| B | VAL171 |
| B | LEU175 |
| B | MET199 |
| B | GLY200 |
| B | LEU203 |
| B | TYR270 |
| B | SER283 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ER4 C 401 |
| Chain | Residue |
| C | PHE45 |
| C | TYR64 |
| C | LEU67 |
| C | ARG68 |
| C | ASP71 |
| C | VAL167 |
| C | ALA168 |
| C | VAL171 |
| C | LEU175 |
| C | TYR179 |
| C | MET199 |
| C | GLY200 |
| C | LEU203 |
| C | SER283 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ER4 D 401 |
| Chain | Residue |
| D | PHE45 |
| D | TYR64 |
| D | LEU67 |
| D | ARG68 |
| D | ASP71 |
| D | ALA168 |
| D | VAL171 |
| D | LEU175 |
| D | TYR179 |
| D | GLY200 |
| D | LEU203 |
| D | SER283 |
| D | HOH545 |
Functional Information from PROSITE/UniProt
| site_id | PS01044 |
| Number of Residues | 16 |
| Details | SQUALEN_PHYTOEN_SYN_1 Squalene and phytoene synthases signature 1. YChyVAGLVGhgLtlL |
| Chain | Residue | Details |
| A | TYR163-LEU178 |
| site_id | PS01045 |
| Number of Residues | 28 |
| Details | SQUALEN_PHYTOEN_SYN_2 Squalene and phytoene synthases signature 2. MGlflQkt.NIiRDFyeDicevpp.RvFwP |
| Chain | Residue | Details |
| A | MET199-PRO226 |
