3W8H
Crystal structure of CCM3 in complex with the C-terminal regulatory domain of STK25
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Programmed cell death protein 10 | polymer | 213 | 24896.6 | 1 | UniProt (Q9BUL8) Pfam (PF20929) Pfam (PF06840) In PDB | Homo sapiens (human) | Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15 |
2 | B | Serine/threonine-protein kinase 25 | polymer | 78 | 8607.7 | 1 | UniProt (O00506) Pfam (PF20929) In PDB | Homo sapiens (human) | Ste20-like kinase, Sterile 20/oxidant stress-response kinase 1, SOK-1, Ste20/oxidant stress response kinase 1 |
3 | A, B | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
4 | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A: 8 - 212 (UniProt: Q9BUL8)
B: 355 - 426 (UniProt: O00506)
PDB | External Database | Details |
---|---|---|
Leu 213 | - | expression tag |
Glu 214 | - | expression tag |
His 215 | - | expression tag |
His 216 | - | expression tag |
His 217 | - | expression tag |
His 218 | - | expression tag |
His 219 | - | expression tag |
His 220 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Pro -5 | - | expression tag |
Gly -4 | - | expression tag |
Ser -3 | - | expression tag |
Glu -2 | - | expression tag |
Phe -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 33504.3 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 672.4 | |
All* | Total formula weight | 34176.7 |