3W88
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with SH-1-200
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydroorotate dehydrogenase (fumarate) | polymer | 314 | 34154.3 | 2 | UniProt (Q4D3W2) Pfam (PF01180) | Trypanosoma cruzi | DHOD, DHODase, DHOdehase, Dihydroorotate oxidase |
| 2 | C, SA (A, B) | 5-[4-(6-carboxynaphthalen-2-yl)butyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | non-polymer | 382.4 | 2 | Chemie (W88) PubChem (73167557) | |||
| 3 | AB, BB, CB, D, DB... (B, A) | GLYCEROL | non-polymer | 92.1 | 24 | Chemie (GOL) PubChem (753) | |||
| 4 | EB, FB, Q, R (B, A) | CACODYLATE ION | non-polymer | 137.0 | 4 | Chemie (CAC) PubChem (167250) | |||
| 5 | GB, S (B, A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 2 | Chemie (FMN) PubChem (710) PubChem (8965) PubChem (643976) PubChem (5702760) PubChem (7048779) PubChem (7048781) PubChem (23585816) PubChem (51435500) PubChem (51435503) PubChem (15559251) | |||
| 6 | AA, BA, CA, DA, EA... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 33 | Chemie (EDO) | |||
| 7 | LA, MA, NA, OA, PA... (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 8 | Chemie (PEG) PubChem (8117) | |||
| 8 | QA, RA (A) | COBALT HEXAMMINE(III) | non-polymer | 161.1 | 2 | Chemie (NCO) | |||
| 9 | AC, ZB (B, A) | water | water | 18.0 | 811 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 312 (UniProt: Q4D3W2)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68308.6 | |
| Non-Polymers* | Number of molecules | 75 |
| Total formula weight | 7655.1 | |
| All* | Total formula weight | 75963.7 |
