3W6P

Crystal structure of human Dlp1 in complex with GDP.AlF4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dynamin-1-like protein	polymer	364	40542.5	2	UniProt (O00429) Pfam (PF00350) Pfam (PF01031)	Homo sapiens (human)	Dnm1p/Vps1p-like protein, DVLP, Dynamin family member proline-rich carboxyl-terminal domain less, Dymple, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, HdynIV, Dynamin-related protein 1
2	C, G (A, B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
3	D, H (A, B)	TETRAFLUOROALUMINATE ION	non-polymer		103.0	2	Chemie (ALF)
4	E, I (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	F, J (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
6	K (B)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
7	L, M (B)	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
8	N, O (A, B)	water	water		18.0	704	Chemie (HOH)

Sequence modifications

A, B: 1 - 329 (UniProt: O00429)

PDB	External Database	Details
Gly -1	-	expression tag
Pro 0	-	expression tag

A, B: 709 - 736 (UniProt: O00429)

PDB	External Database	Details
His 330	-	linker
Gly 331	-	linker
Thr 332	-	linker
Asp 333	-	linker
Ser 334	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	81085.0
Non-Polymers*	Number of molecules	11
	Total formula weight	1615.5
All*	Total formula weight	82700.4

*Water molecules are not included.