3W18
Structure of Aurora kinase A complexed to benzoimidazole-indazole inhibitor XIII
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aurora kinase A | polymer | 278 | 32214.9 | 2 | UniProt (O14965) Pfam (PF00069) | Homo sapiens (human) | Aurora 2, Aurora/IPL1-related kinase 1, ARK-1, Aurora-related kinase 1, hARK1, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, Serine/threonine-protein kinase aurora-A |
| 2 | C, D (A, B) | 2-{3-[3-(1H-benzimidazol-2-yl)-1H-indazol-6-yl]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide | non-polymer | 451.5 | 2 | Chemie (N13) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64429.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 902.9 | |
| All* | Total formula weight | 65332.7 |
