3VXV
Crystal structure of methyl CpG Binding Domain of MBD4 in complex with the 5mCG/TG sequence
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methyl-CpG-binding domain protein 4 | polymer | 69 | 7829.1 | 1 | UniProt (Q9Z2D7) Pfam (PF01429) | Mus musculus (mouse) | Methyl-CpG-binding protein MBD4, Mismatch-specific DNA N-glycosylase |
| 2 | B (B) | DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*CP*(5CM)P*GP*GP*AP*CP*A)-3') | polymer | 14 | 4263.8 | 1 | |||
| 3 | C (C) | DNA (5'-D(*GP*TP*CP*TP*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3') | polymer | 14 | 4326.8 | 1 | |||
| 4 | D, E, K (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 5 | F, G, H, I, J... (A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | M, N, O (A, B, C) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A: 69 - 136 (UniProt: Q9Z2D7)
| PDB | External Database | Details |
|---|---|---|
| Ser 68 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 16419.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 549.5 | |
| All* | Total formula weight | 16969.3 |
