3VW9
Human Glyoxalase I with an N-hydroxypyridone inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Lactoylglutathione lyase | polymer | 187 | 21086.0 | 2 | UniProt (Q04760) Pfam (PF00903) In PDB | Homo sapiens (human) | Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 4 | A, B | 1-hydroxy-6-[1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-4-phenylpyridin-2(1H)-one | non-polymer | 375.4 | 2 | Chemie (HPJ) | |||
| 5 | water | water | 18.0 | 542 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 183 (UniProt: Q04760)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42172.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1120.0 | |
| All* | Total formula weight | 43291.9 |
