3VW6
Crystal structure of human apoptosis signal-regulating kinase 1 (ASK1) with imidazopyridine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mitogen-activated protein kinase kinase kinase 5 | polymer | 269 | 30297.6 | 2 | UniProt (Q99683) Pfam (PF00069) | Homo sapiens (human) | Apoptosis signal-regulating kinase 1, ASK-1, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5 |
| 2 | C, D (A, B) | 4-tert-butyl-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide | non-polymer | 359.4 | 2 | Chemie (IM6) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60595.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 718.8 | |
| All* | Total formula weight | 61314.1 |
