3VUZ
Crystal structure of histone methyltransferase SET7/9 in complex with AAM-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase SETD7 | polymer | 263 | 29083.2 | 1 | UniProt (Q8WTS6) Pfam (PF22648) Pfam (PF00856) | Homo sapiens (human) | Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET7/9 |
| 2 | B (A) | 5'-{[(3S)-3-amino-3-carboxypropyl](hexyl)amino}-5'-deoxyadenosine | non-polymer | 451.5 | 1 | Chemie (K15) | |||
| 3 | C (A) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A: 111 - 366 (UniProt: Q8WTS6)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Gly 4 | - | expression tag |
| Ser 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Gly 7 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29083.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 451.5 | |
| All* | Total formula weight | 29534.8 |
