3VU7

Crystal structure of REV1-REV7-REV3 ternary complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	DNA repair protein REV1	polymer	124	14095.1	1	UniProt (Q9UBZ9) Pfam (PF16727) In PDB	Homo sapiens (human)	Alpha integrin-binding protein 80, AIBP80, Rev1-like terminal deoxycytidyl transferase
2	C	Mitotic spindle assembly checkpoint protein MAD2B	polymer	227	26101.2	1	UniProt (Q9UI95) Pfam (PF02301) In PDB	Homo sapiens (human)	Mitotic arrest deficient 2-like protein 2, MAD2-like protein 2, REV7 homolog, hREV7
3	Z	DNA polymerase zeta catalytic subunit	polymer	52	5632.3	1	UniProt (O60673) In PDB	Homo sapiens (human)	Protein reversionless 3-like, REV3-like, hREV3

Sequence modifications

H: 1140 - 1251 (UniProt: Q9UBZ9)

PDB	External Database	Details
Met 1128	-	expression tag
Arg 1129	-	expression tag
Gly 1130	-	expression tag
Ser 1131	-	expression tag
His 1132	-	expression tag
His 1133	-	expression tag
His 1134	-	expression tag
His 1135	-	expression tag
His 1136	-	expression tag
His 1137	-	expression tag
Gly 1138	-	expression tag
Ser 1139	-	expression tag

C: 1 - 211 (UniProt: Q9UI95)

PDB	External Database	Details
Met -15	-	expression tag
Gly -14	-	expression tag
Ser -13	-	expression tag
Ser -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Ser -5	-	expression tag
Gln -4	-	expression tag
Asp -3	-	expression tag
Pro -2	-	expression tag
Asn -1	-	expression tag
Ser 0	-	expression tag
Ala 124	Arg 124	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	45828.7
All*	Total formula weight	45828.7

*Water molecules are not included.