3VRP
Crystal structure of the tyrosine kinase binding domain of Cbl-c in complex with phospho-EGFR peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Signal transduction protein CBL-C | polymer | 331 | 36691.1 | 1 | UniProt (Q9ULV8) Pfam (PF02262) Pfam (PF02761) Pfam (PF02762) In PDB | Homo sapiens (human) | RING finger protein 57, SH3-binding protein CBL-3, SH3-binding protein CBL-C |
2 | B | Epidermal growth factor receptor | polymer | 13 | 1625.6 | 1 | UniProt (P00533) In PDB | Homo sapiens | Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 |
3 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
4 | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
A: 1 - 323 (UniProt: Q9ULV8)
PDB | External Database | Details |
---|---|---|
Gly -7 | - | EXPRESSION TAG |
Pro -6 | - | EXPRESSION TAG |
Leu -5 | - | EXPRESSION TAG |
Gly -4 | - | EXPRESSION TAG |
Ser -3 | - | EXPRESSION TAG |
Pro -2 | - | EXPRESSION TAG |
Glu -1 | - | EXPRESSION TAG |
Phe 0 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 38316.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 40.1 | |
All* | Total formula weight | 38356.7 |