3VQH
Bromine SAD partially resolves multiple binding modes for PKA inhibitor H-89
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 351 | 40888.5 | 1 | UniProt (P17612) Pfam (PF00069) | Homo sapiens (human) | PKA C-alpha |
| 2 | B (B) | cAMP-dependent protein kinase inhibitor alpha | polymer | 20 | 2226.4 | 1 | UniProt (P61925) | Homo sapiens | PKI-alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform |
| 3 | C (A) | N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE | non-polymer | 446.4 | 1 | Chemie (IQB) | |||
| 4 | D (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43115.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 564.5 | |
| All* | Total formula weight | 43679.5 |
