3VP1
Crystal structure of human glutaminase in complex with L-glutamate and BPTES
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glutaminase kidney isoform, mitochondrial | polymer | 315 | 34688.6 | 1 | UniProt (O94925) Pfam (PF04960) In PDB | Homo sapiens (human) | GLS, K-glutaminase, L-glutamine amidohydrolase |
| 2 | A | N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) | non-polymer | 524.7 | 1 | Chemie (04A) | |||
| 3 | A | GLUTAMIC ACID | non-polymer | 147.1 | 1 | Chemie (GLU) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A: 221 - 533 (UniProt: O94925)
| PDB | External Database | Details |
|---|---|---|
| Ser 219 | - | expression tag |
| Met 220 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34688.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 863.9 | |
| All* | Total formula weight | 35552.5 |
