3VP1
Crystal structure of human glutaminase in complex with L-glutamate and BPTES
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 04A A 601 |
| Chain | Residue |
| A | ARG317 |
| A | ARG317 |
| A | PHE318 |
| A | LYS320 |
| A | PHE322 |
| A | PHE322 |
| A | LEU323 |
| A | ASN324 |
| A | TYR394 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GLU A 602 |
| Chain | Residue |
| A | TYR249 |
| A | GLN285 |
| A | SER286 |
| A | ASN335 |
| A | GLU381 |
| A | ASN388 |
| A | TYR414 |
| A | TYR466 |
| A | VAL484 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 603 |
| Chain | Residue |
| A | PHE373 |
| A | SER374 |
| A | ASN375 |
| A | ASN375 |
| A | ALA376 |
| A | ALA376 |
| A | HOH726 |
| A | HOH726 |
| A | HOH762 |
| A | HOH762 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 604 |
| Chain | Residue |
| A | LYS320 |
| A | ARG387 |
| A | TYR394 |
| A | LYS398 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22049910, ECO:0000269|PubMed:22538822, ECO:0000305|PubMed:24451979, ECO:0007744|PDB:3CZD, ECO:0007744|PDB:3UNW, ECO:0007744|PDB:3VP0, ECO:0007744|PDB:3VP1 |
| Chain | Residue | Details |
| A | SER286 | |
| A | ASN335 | |
| A | GLU381 | |
| A | TYR414 | |
| A | TYR466 | |
| A | VAL484 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22049910, ECO:0000269|PubMed:22538822, ECO:0000305|PubMed:24451979, ECO:0007744|PDB:3CZD, ECO:0007744|PDB:3UNW, ECO:0007744|PDB:3VP1 |
| Chain | Residue | Details |
| A | ASN388 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS311 |
