3VN9
Rifined Crystal structure of non-phosphorylated MAP2K6 in a putative auto-inhibition state
Replaces: 3AN0Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dual specificity mitogen-activated protein kinase kinase 6 | polymer | 340 | 38369.2 | 1 | UniProt (P52564) Pfam (PF00069) In PDB | Homo sapiens (human) | MAP kinase kinase 6, MAPKK 6, MAPK/ERK kinase 6, MEK 6, Stress-activated protein kinase kinase 3, SAPK kinase 3, SAPKK-3, SAPKK3 |
2 | A | 9-{5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-beta-L-ribofuranosyl}-9H-purin-6-amine | non-polymer | 506.2 | 1 | Chemie (ANK) | |||
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A: 1 - 334 (UniProt: P52564)
PDB | External Database | Details |
---|---|---|
His 335 | - | expression tag |
His 336 | - | expression tag |
His 337 | - | expression tag |
His 338 | - | expression tag |
His 339 | - | expression tag |
His 340 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 38369.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 530.5 | |
All* | Total formula weight | 38899.7 |