3VI7
Human hematopoietic prostaglandin D synthase inhibitor complex structures
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Hematopoietic prostaglandin D synthase | polymer | 198 | 23256.7 | 4 | UniProt (O60760) Pfam (PF02798) Pfam (PF14497) In PDB | Homo sapiens (human) | H-PGDS, GST class-sigma, Glutathione S-transferase, Glutathione-dependent PGD synthase, Glutathione-requiring prostaglandin D synthase, Prostaglandin-H2 D-isomerase |
| 2 | A, B, C, D | GLUTATHIONE | non-polymer | 307.3 | 4 | Chemie (GSH) | |||
| 3 | A, B | CIBACRON BLUE | non-polymer | 774.2 | 2 | Chemie (CBD) | |||
| 4 | C, D | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | water | water | 18.0 | 743 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 199 (UniProt: O60760)
| PDB | External Database | Details |
|---|---|---|
| Met 144 | Asn 144 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93026.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2857.8 | |
| All* | Total formula weight | 95884.7 |
