3VHK
Crystal structure of the VEGFR2 kinase domain in complex with a back pocket binder
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vascular endothelial growth factor receptor 2 | polymer | 368 | 41804.8 | 1 | UniProt (P35968) Pfam (PF07714) | Homo sapiens (human) | VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1 |
| 2 | B (A) | {3-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]phenyl}methanol | non-polymer | 295.3 | 1 | Chemie (BPK) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A: 806 - 1171 (UniProt: P35968)
| PDB | External Database | Details |
|---|---|---|
| Gly 804 | - | expression tag |
| Ala 805 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41804.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 357.4 | |
| All* | Total formula weight | 42162.2 |
