3VHA
Hsp90 alpha N-terminal domain in complex with a macrocyclic inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Heat shock protein HSP 90-alpha | polymer | 229 | 25788.0 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | Homo sapiens (human) | Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38 |
2 | A | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
3 | A | 22-methyl-13,18-dioxa-7-thia-3,5-diazatetracyclo[17.3.1.1~2,6~.1~8,12~]pentacosa-1(23),2(25),3,5,8(24),9,11,19,21-nonaen-4-amine | non-polymer | 379.5 | 1 | Chemie (VHA) | |||
4 | water | water | 18.0 | 316 | Chemie (HOH) |
Sequence modifications
A: 9 - 236 (UniProt: P07900)
PDB | External Database | Details |
---|---|---|
Met 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 25788.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 574.7 | |
All* | Total formula weight | 26362.7 |