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3VH4

Crystal structure of Atg7CTD-Atg8-MgATP complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ubiquitin-like modifier-activating enzyme ATG7polymer34038150.91UniProt (P38862)
Pfam (PF00899)
Saccharomyces cerevisiae (Baker's yeast)ATG12-activating enzyme E1 ATG7, Autophagy-related protein 7, Cytoplasm to vacuole targeting protein 2
2B
(B)
Autophagy-related protein 8polymer11913751.91UniProt (P38182)
Pfam (PF02991)
Saccharomyces cerevisiae (Baker's yeast)Autophagy-related ubiquitin-like modifier ATG8, Cytoplasm to vacuole targeting protein 5
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D
(A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
5E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence modifications
A: 295 - 630 (UniProt: P38862)
PDBExternal DatabaseDetails
Gly 291-expression tag
Pro 292-expression tag
His 293-expression tag
Met 294-expression tag
B: 1 - 116 (UniProt: P38182)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Pro 26Lys 26engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight51902.7
Non-Polymers*Number of molecules3
Total formula weight596.9
All*Total formula weight52499.6
*Water molecules are not included.

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PDB entries from 2024-11-13

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