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3VH4

Crystal structure of Atg7CTD-Atg8-MgATP complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0008641molecular_functionubiquitin-like modifier activating enzyme activity
B0000045biological_processautophagosome assembly
B0000329cellular_componentfungal-type vacuole membrane
B0000407cellular_componentphagophore assembly site
B0000421cellular_componentautophagosome membrane
B0000422biological_processautophagy of mitochondrion
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005773cellular_componentvacuole
B0005774cellular_componentvacuolar membrane
B0005776cellular_componentautophagosome
B0005829cellular_componentcytosol
B0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
B0006914biological_processautophagy
B0006995biological_processcellular response to nitrogen starvation
B0008429molecular_functionphosphatidylethanolamine binding
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0016241biological_processregulation of macroautophagy
B0031386molecular_functionprotein tag activity
B0031410cellular_componentcytoplasmic vesicle
B0031503biological_processprotein-containing complex localization
B0031625molecular_functionubiquitin protein ligase binding
B0031966cellular_componentmitochondrial membrane
B0032258biological_processcytoplasm to vacuole targeting by the Cvt pathway
B0033110cellular_componentCvt vesicle membrane
B0034497biological_processprotein localization to phagophore assembly site
B0034727biological_processpiecemeal microautophagy of the nucleus
B0044804biological_processnucleophagy
B0061025biological_processmembrane fusion
B0061709biological_processreticulophagy
B0071211biological_processprotein targeting to vacuole involved in autophagy
B0097352biological_processautophagosome maturation
B0120095cellular_componentvacuole-isolation membrane contact site
B1905153biological_processregulation of membrane invagination
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 701
ChainResidue
ACYS485
ACYS488
ACYS569
ACYS572

site_idAC2
Number of Residues13
DetailsBINDING SITE FOR RESIDUE ATP A 702
ChainResidue
AASN363
AGLN367
ALYS379
ALEU401
AILE403
AASP438
AMG703
BGLY116
AGLY333
ATHR334
AASP355
AASN356
AGLY357

site_idAC3
Number of Residues2
DetailsBINDING SITE FOR RESIDUE MG A 703
ChainResidue
AASP438
AATP702

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Cleavage; by ATG4 => ECO:0000269|PubMed:11038174
ChainResidueDetails
BGLY116

site_idSWS_FT_FI2
Number of Residues1
DetailsLIPID: Phosphatidylethanolamine amidated glycine => ECO:0000269|PubMed:11100732
ChainResidueDetails
BGLY116

218853

PDB entries from 2024-04-24

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