3VD0

structure of p73 DNA binding domain tetramer modulates p73 transactivation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, I...	Tumor protein p73	polymer	210	23776.0	8	UniProt (O15350) Pfam (PF00870) In PDB	Homo sapiens (human)	p53-like transcription factor, p53-related protein
2	E, F, G, H, M...	DNA (5'-D(*CP*AP*GP*GP*CP*AP*TP*GP*CP*CP*TP*G)-3')	polymer	12	3663.4	8
3	A, B, C, D, I...	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
4		water	water		18.0	169	Chemie (HOH)

Sequence modifications

A, B, C, D, I, J, K, L: 115 - 312 (UniProt: O15350)

PDB	External Database	Details
Met 103	-	initiating methionine
Gly 104	-	expression tag
His 105	-	expression tag
His 106	-	expression tag
His 107	-	expression tag
His 108	-	expression tag
His 109	-	expression tag
His 110	-	expression tag
His 111	-	expression tag
His 112	-	expression tag
Glu 113	-	expression tag
Phe 114	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	219514.8
Non-Polymers*	Number of molecules	8
	Total formula weight	523.3
All*	Total formula weight	220038.0

*Water molecules are not included.