3VD0

structure of p73 DNA binding domain tetramer modulates p73 transactivation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006915	biological_process	apoptotic process
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005634	cellular_component	nucleus
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006915	biological_process	apoptotic process
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0005634	cellular_component	nucleus
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006915	biological_process	apoptotic process
D	0000976	molecular_function	transcription cis-regulatory region binding
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0005634	cellular_component	nucleus
D	0006355	biological_process	regulation of DNA-templated transcription
D	0006915	biological_process	apoptotic process
I	0000976	molecular_function	transcription cis-regulatory region binding
I	0003677	molecular_function	DNA binding
I	0003700	molecular_function	DNA-binding transcription factor activity
I	0005634	cellular_component	nucleus
I	0006355	biological_process	regulation of DNA-templated transcription
I	0006915	biological_process	apoptotic process
J	0000976	molecular_function	transcription cis-regulatory region binding
J	0003677	molecular_function	DNA binding
J	0003700	molecular_function	DNA-binding transcription factor activity
J	0005634	cellular_component	nucleus
J	0006355	biological_process	regulation of DNA-templated transcription
J	0006915	biological_process	apoptotic process
K	0000976	molecular_function	transcription cis-regulatory region binding
K	0003677	molecular_function	DNA binding
K	0003700	molecular_function	DNA-binding transcription factor activity
K	0005634	cellular_component	nucleus
K	0006355	biological_process	regulation of DNA-templated transcription
K	0006915	biological_process	apoptotic process
L	0000976	molecular_function	transcription cis-regulatory region binding
L	0003677	molecular_function	DNA binding
L	0003700	molecular_function	DNA-binding transcription factor activity
L	0005634	cellular_component	nucleus
L	0006355	biological_process	regulation of DNA-templated transcription
L	0006915	biological_process	apoptotic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 401

Chain	Residue
A	CYS194
A	HIS197
A	CYS258
A	CYS262

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 401

Chain	Residue
B	CYS194
B	HIS197
B	CYS258
B	CYS262

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 401

Chain	Residue
C	HIS197
C	CYS258
C	CYS262
C	CYS194

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 401

Chain	Residue
D	CYS194
D	HIS197
D	CYS258
D	CYS262

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN I 401

Chain	Residue
I	CYS194
I	HIS197
I	CYS258
I	CYS262

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN J 401

Chain	Residue
J	CYS194
J	HIS197
J	CYS258
J	CYS262

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN K 401

Chain	Residue
K	CYS194
K	HIS197
K	CYS258
K	CYS262

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 401

Chain	Residue
L	CYS194
L	HIS197
L	CYS258
L	CYS262

---

Functional Information from PROSITE/UniProt

site_id	PS00348
Number of Residues	13
Details	P53 p53 family signature. MCNSSCVGGMNRR

Chain	Residue	Details
A	MET257-ARG269

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1432
Details	Region: {"description":"DNA-binding","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	32
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---